Wet the skin with water, then rub the soap between your hands or directly on the face or body until a light lather forms. Massage gently in circular motions, then rinse thoroughly with lukewarm water. Current papaya-soap usage sources commonly describe it as suitable for face and body, with gentle daily or regular use depending on skin tolerance.

If you have sensitive skin, start slowly and do a patch test first. Papaya soap is often described as mildly exfoliating because of papaya-derived enzymes, so overuse may lead to dryness or irritation in some people.